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Reasons for the different results may include the limited sample sizes, the assays for detection, different stages of the disease, and the difference between local and systemic states of oxidative stress

Dranka BP, Gifford A, Ghosh A, Zielonka J, Joseph J, Kanthasamy AG, Kalyanaraman B (2013) Diapocynin prevents early Parkinsons disease symptoms in the leucine-rich repeat kinase 2 (LRRK2) transgenic mouse

318 Another study evaluated the efficacy of CP31398 in a transgenic UPII-SV40T mouse model of human transitional cell carcinoma (TCC), and the results showed that mice that received CP31398 suppressed invasive TCC

Blog post about being symptomatic for B12 deficiency with normal range serum B12

One downside that some find with water-based lubes is that they dry out quicker when exposed to air, as opposed to silicone, oil, or hybrids, so they might not be great for, say, foreplay