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Enteroendocrine cells distributed along the intestinal lining sense luminal nutrients and microbial metabolites and release hormones and neuropeptides that act both locally and systemically

The action of gremubamab is bivalent in that it targets not only the TS33 but also the adhesin Psl exopolysaccharide in P

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In the iris, CTGF is observed in both the sphincter and dilator muscles, and in the vessels of the iris and ciliary body, where it is derived from vascular endothelium but not from vascular smooth muscle cells (83)