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Metabolomics and lipidomics was performed and analysed by Metabolomics Platform from University of Chicago Medicine Comprehensive Cancer Center (RRID: SCR_022932) supported by H

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Therefore, to meet practical demands, the rational design of AIE phototheranostic systems and manipulating their absorbed photon energy dissipation for generating fluorescence for imaging, ROS for PDT and heat for PAI/PTT according to practical demand are important and will be discussed

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