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Oxid Med Cell Longev 2020(1):5021694 Emudainohwo JO et al (2023) Normalization of HPA axis, cholinergic neurotransmission, and inhibiting brain oxidative and inflammatory dynamics are associated with the adaptogenic-like effect of rutin against psychosocial defeat stress

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The basis for this presumption is the fact that the synthesis of the Gpx3-Yap1 intermediate relies on the existence of Ybp1 (Tomalin, 2015

McGraw-Hill Education, New York Kanner BI, Schuldiner S (1987) Mechanism of transport and storage of neurotransmitter

However, in contrast to the maternal reproductive tract, insufficient antioxidant levels in the in vitro culture environment, weakening of the cellular antioxidant mechanism, or excessive cellular oxygen production for various reasons, resulting in increased ROS accumulation, are the cause of oxidative stress 19,20,24