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Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial

doi: 10.1074/mcp.TIR120.002048 88 KimHJKimTHoffmanNJXiaoDJamesDEHumphreySJet al

B 13, 15481572

Due to the plasticity of the peripheral nervous system, murine salivary glands become reinnervated over time, as shown by the reappearance of TUBB3 + nerves 30 days after transection (Appendix Fig S2A) and reexpression of the neuronal genes Tubb3 , Vip, and Vacht (Fig 3B, blue bars