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Neuropharmacology 108, 179192

For instance, in a pilot phase-I clinical study by Dorr et al., three subjects were subcutaneously administered a starting dose of 0.01 mg/kg of MT-II, followed by daily injections of MT-II or placebo for two consecutive weeks

Massons trichrome staining was conducted to assess collagen deposition and fibrosis, with tissue sections subjected to Weigerts iron hematoxylin (R20387, Shanghai yuanye Bio-Technology Co., Ltd., China), Ponceau S acid fuchsin stain (71019360, 71033761, Sinopharm Chemical Reagent Co., Ltd., China), and Aniline blue (71003644, Sinopharm Chemical Reagent Co., Ltd., China) staining solutions

This is a key paper linking the ECM of fibroids to its functional significance in this disease

Low levels may cause mood swings, irritability, or even a sense of persistent low spirits