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Description

2b,c and Extended Data Fig

NICE, London Nottinghamshire Area Prescribing Committee (2023) Vitamin B12 treatment guideline

[4] Based on animal research, it is thought that the increased methylmalonyl-CoA hydrolyzes to form methylmalonate (methylmalonic acid), a neurotoxic dicarboxylic acid, causing neurological deterioration

It acts mainly on beta-3-adrenergic receptors located in fat tissue , which translates into high burning efficiency without a negative impact on other systems