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Description

After blocking, the membranes were incubated with mouse anti-GST (Santa Cruz Biotechnology), TG2 7 , and FLAG antibodies (Sigma-Aldrich) at 4 C overnight

With the comprehensive elucidation of the mechanisms underlying natural products and the advancement of synthetic biology technologies, radiation protection strategies that leverage the multi-target synergy and low toxicity of natural compounds are anticipated to address precision bias bottlenecks, facilitate the introduction of new products such as nanoformulations into clinical applications, and ultimately deliver highly efficient and safe solutions for nuclear protection and aerospace medicine

As a mediator of cancer cachexia syndrome, IL-6 activates the IL-6/JAK/STAT3 pathway to induce TG2 expression in order for tumors to acquire an EMT phenotype (124, 138)