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PMID 17289424

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To date, nucleotides are primarily prepared by chemical methods such as the Yoshikawa protocol or the Ludwig-Eckstein method ( Biocatalytic routes exploiting enzymes from the nucleotide metabolism promise improved regioselectivity and exquisite control over the phosphorylation product

has consulting or advisory roles with AbbVie, Adaptive, Amgen, Aptitude Health, Bristol Myers Squibb, GlaxoSmithKline, Huron Consulting, Janssen, Menarini Silicon Biosystems, Oncopeptides, Pfizer, Sanofi, Sognef, Takeda, The Binding Site and Window Therapeutics