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However, DNA demethylating agents, such as 5-aza-CdR, Zebularine, or the oligonucleotide antisense inhibitor of DNMT1, MG98 (Plummer et al., 2009), may be considered as FRDA therapeutic options in the future

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A lack of nitric oxide is associated with heart disease, diabetes, high blood pressure, and sexual dysfunction. This benefit of chlorella may explain some of the health claims associated with the supplement

Funding This research was supported by the INSERM, Universit Cte dAzur, the Fondation ARC pour la Recherche contre le Cancer (Equipe Labellise 20222025), the Canceropole PACA, a grant from PLBio (R19003AP-20192023), ITMO cancer 20192023 and the Association Laurette Fugain (ALF)

While they share some overlapping areas of investigation, they differ significantly in structure, origin, and proposed mechanisms