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Bride KL, Vincent TL, Im S-Y, Aplenc R, Barrett DM, Carroll WL, et al

Vitamin C (ascorbic acid) supplements: Taking vitamin B12 along with vitamin C can reduce the amount of vitamin B12 available in the body

Cyanocobalamin, a synthetic version of Vitamin B12, comes from a complex bacterial process

2 mg SC daily for HIV lipodystrophy

These interactions for 1j might promote tighter binding affinity compared to the endogenous substrate NCA, further indicated by a much lower calculated Vina docking score for 1j (8.1 vs for NCA) that suggests improved energetic interactions for 1j in the NNMT active site