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Mixed evidence: Some supportive human data, but inconsistency or methodological limitations across studies

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While it is reasonable to assume that during network activity both glutamate and K + increase in the environment of astrocytes, the precise timing and/or concentration-dependencies of the effects of the different signals particularly in the brain in vivo needs further investigation

Both groups then received an injection of fentanyl (75 g/kg, IV) and BT was recorded 5, 10, 15, 20, 25 and 30 min later

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