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[14] These include peripheral neuropathy, epilepsy, headache, encephalopathy, vascular dementia, and various movement disorders (restless legs syndrome, chorea, parkinsonism, Tourette syndrome, palatal tremor, myoclonus, dystonia, opsoclonus myoclonus syndrome, paroxysms, dyskinesia, myorhythmia, myokymia)

However, CagriSema also fell short of the companys own expectations that it would achieve at least 25% weight loss

In agreement, the amount of Cyclin D1 protein was strongly induced in the WT regenerating livers from 36 to 48 h prior the onset of DNA synthesis while its expression gradually increased in a time-dependent manner leading to the maximal levels after only 55 h in the Gstp1/2 / livers (Figures 5b and c)