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Variant reclassification and clinical implications

Clinical signs of aflatoxicosis are non-pruritic macular rash, headache, gastrointestinal dysfunction (often extreme), lower extremity edema, anemia, and jaundice OCHRATOXIN A- a nephrotoxic, immunotoxic, and carcinogenic mycotoxin

The warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation

The histone H2A deubiquitinase USP16 interacts with HERC2 and fine-tunes cellular response to DNA damage

Finasteride: reminder of the risk of psychiatric side effects and of sexual side effects which may persist after discontinuation of treatment