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PD-linked CHCHD2 mutations impair CHCHD10 and MICOS complex leading to mitochondria dysfunction

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Ernest Ward, DVM Dilated Cardiomyopathy in Dogs (DCM) Genetics of Human and Canine Dilated Cardiomyopathy by Siobhan Simpson, Jennifer Edwards, Thomas F

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In order to exclude any virus-dependent effects, we further investigated the T cell-dependent (TD) response in Gclc fl/fl Mb1-Cre + mice using a stronger, T cell-driven model of cytopathic viral infection