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After 24 hours, both the double and the triple combinations increased cell death

183 The main characteristics of HSC senescence include a decrease in self-renewal ability, an imbalance in differentiation bias, and epigenetic abnormalities

Interestingly, the GltT-defective mutant also exhibited less adhesive and invasive properties to human bronchial epithelial cells, and transcriptome analysis suggested that genetic inactivation of gltT led to remodeling of the outer membrane and surface structures (Li et al., 2009)