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For example, it ameliorates motor dysfunction in Parkinsons disease (PD) model rats by reducing striatal extracellular glutamate (Glu) concentrations (Shi et al., 2019)

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Consequently, researchers have put forward the concept of combination therapy for cancer treatment, which refers to the therapeutic agents co-administrated for the treatment of cancer ( Although combination therapies contribute to better cancer treatment to some extent, current combination therapies also have many shortcomings: owing to heterogeneity in the physicochemical properties and pharmacokinetics of diverse therapeutic agents, the amount of these therapeutic agents actually reaching the tumor site differs greatly when the prescribed dose is administered, making it difficult to achieve accurate control of the synergistic ratio

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