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Comparative analysis of two NNMT bisubstrate inhibitors through chemoproteomic studies: uncovering the role of unconventional SAM analogue moiety for improved selectivity

Though peptides are sensitive to moisture and temperature changes, many are stable in cool, dry conditions, away from light

Studies show that inhibiting nicotinamide Nmethyltransferase (NNMT) enhances metabolic health by reducing adipose tissue accumulation, improving insulin sensitivity, and promoting better energy utilization

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doi: 10.1042/0264-6021:3510183 57 SchockBCYoungISBrownVFitchPSShieldsMDEnnisM