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Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress

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While the molecular ruthenium catalyst and the nanoreactors without carbon fluorinated moieties were cytotoxic in the low micromolar range in a 21% O 2 atmosphere, these compounds lost their therapeutic effect in a 1% O 2 atmosphere

doi: 10.1155/2015/282375 152 LeeJHKangYEChangJYParkKCKimH-WKimJTet al

It has been administered by intranasal and intrabronchial routes as well