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In this mechanism, L-carnitine is acylated with activated LCFA by carnitine-palmitoyl transferase 1, which is located on the outer mitochondrial membrane (4)

(4) What study designs were used to answer research questions

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Before each treatment, cells were cultured for 5 days in vitro in Neurobasal medium supplemented with 2% v/v B-27 medium, with 0.5 mM L-glutamine and with penicillinstreptomycin (50 mg/ml of each) and were maintained at 37 C in a 5% CO2 atmosphere

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