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Intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, aortal hypotension, progressing venous and arterial thrombosis peripherally and centrally, and ECG disturbances [14,15,16,20,22,23,24,25] were commonly counteracted

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4C) and higher specific activity for ( S )-GS-HPV than the wild type (Fig

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