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Description

While these pathway inefficiencies have been demonstrated in autism, it is likely that similar defects will affect older individuals and may present with a different set of symptoms

Undoubtedly, eukaryotic cells have complex system of enzymatic antioxidants such as superoxide dismutase-1, 2 and 3 (SODs), catalase, glutathione peroxidase (GPx)

They effectively reach specific cells before releasing their contents

Statistical analyses Analyses were conducted using JMP16 for Windows

Mechanistically, this inhibition of glycolytic activity was attributable to destabilization of HIF-1 protein, possibly through -KG-dependent PHD enzyme-mediated hydroxylation and enhanced degradation of HIF-1 protein (33)