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Enrichment analysis was performed to identify significantly altered metabolic pathways

Glycometabolism in macrophages Proinflammatory M1 macrophages have higher glucose consumption and lactate release than M2 macrophages, mainly relying on aerobic glycolysis, while anti-inflammatory M2 macrophages mainly rely on oxidative phosphorylation (OXPHOS)

210,211,212 In recent studies, NIR irradiation for BBB permeability regulation was applied under infrared thermal monitoring and the head temperature was kept lower than 43 C

Diazepam is preferentially absorbed in the stomach, due to its increased solubility in acidic pH, making it an ideal candidate for gastric retention

Stored properly in its sealed vial at cool temperatures, lyophilized BPC-157 can remain stable for months or even years