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Modern pharmacology indicates its efficacy includes antitumor activity, enzyme-lowering activity, and anti-fibrotic activity [174]

Furthermore, dyslipidemia in pSS has been associated with several demographic factors, including gender, age, smoking status, and disease activity, with more pronounced lipid abnormalities observed in patients with heightened autoimmune responses and elevated inflammation levels [60]

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doi: 10.1038/nrn2515 82

In db/db mice, the administration of BHB was shown to increase the levels of autophagy markers, including LC3 (Map1lc3a), p62 (Sqstm1), and beclin (Atg6), as well as enhance autophagic flux in the kidneys [9]