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ONC201 Induces p53-independent Apoptosis and Abrogates Stem Cell Function in Hematological Malignancies by Induction of ATF4 Through Integrated Stress Response

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To view a copy of this licence, visit About this article Cite this article Rossi, A., Simeoli, C., Pivonello, R

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Research models with baseline HbA1c above 6.0% or fasting glucose above 110 mg/dL should not initiate this protocol without continuous glucose monitoring, as MK-677 specifically has been shown to increase fasting glucose by 58 mg/dL and HbA1c by 0.30.5% even in metabolically healthy subjects