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RNA isolation and qPCR analysis Total RNA from skin and lungs was isolated by RNeasy Fibrous tissue mini kits (Qiagen, Germantown, MD, 74,704)

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The first therapeutic mAb, Daratumumaba fully human immunoglobulin (IgG)delivered strong trial results and was rapidly approved by the American FDA for in vivo use, with Janssen as the drug provider

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