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Nitric oxide donor prevents hydrogen peroxide-mediated endothelial cell injury

International Journal of Sport Nutrition and Exercise Metabolism, 2011

In an MPTP-induced Parkinson's disease animal model, intracerebroventricular injection of PBzyme decreases dopaminergic degradation and inhibits neuroinflammation by downregulating the activation of microglial nucleotide-binding domain and leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasomes and caspase-1 by scavenging reactive oxygen species which ultimately leads to microglia pyroptosis (Ma et al., 2022)

Bioactive self-assembling peptide hydrogels functionalized with brain-derived neurotrophic factor and nerve growth factor mimicking peptides synergistically promote peripheral nerve regeneration

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