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Sindler AL, Delp MD, Reyes R, Wu G, Muller-Delp JM

BCAA overload may activate the mTOR pathway and inhibit the PI3K-Akt intracellular pathway, causing insulin resistance (29, 54)

Small intestinal bacterial overgrowth syndrome

In suicidal NETosis, intracellular NET formation is followed by the rupture of the cell envelope resulting in the NET release into the extracellular surroundings, but also in neutrophil death and the loss of viable cell functions, such as chemotaxis and the ability to phagocytize pathogens