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The highest concentration is located at the level of the lamina cribrosa in order to protect this most vulnerable area of the retina and to ensure an adequate ATP supply (Minckler et al., 1976

(IM only) Taurine is thought to have multiple benefits, however it is known to help metabolize carbohydrates, sugars, and fats in the body

Indeed, excessive ROS production is implicated in tissue injury in IBDmucosal biopsies from active IBD show increased markers of oxidative damage (109), and patients often have elevated levels of ROS byproducts (110, 111)

Supernatant was collected following a 14K x g spin at 4C

GPx4 was found to be rigid except for a short loop region