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BBB has restricted the adjuvant treatment of brain tumors with chemotherapeutic agents introduced systemically

Isoxazole 1 - Cn Acs1: The complex with isoxazole 1 was prepared by adding the inhibitor, from a 100 mM stock in DMSO, to an aliquot of the protein to a final concentration of 2 mM and incubating for 30 min on ice

J., Flammer, A

Liu XD, Hoang A, Zhou L, Kalra S, Yetil A, Sun M, Ding Z, Zhang X, Bai S, German P, Tamboli P, Rao P, Karam JA, Wood C, Matin S, Zurita A, Bex A, Griffioen AW, Gao J, Sharma P, Tannir N, Sircar K, Jonasch E

qPCR was performed on the CFX96 Touch Real-Time PCR Detection System (Bio-Rad) using SYBR Green reagent (Roche)