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While most therapies aim to downregulate neutrophils to prevent protease damage, inhaled GM-CSF aims to restore or enhance neutrophil bactericidal function, which may be beneficial for clearing persistent infections like NTM A phase 1 randomized, double-blind, placebo-controlled clinical trial (NCT02468908) involving healthy adults has been completed in the UK

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Investigation of the antioxidant status in multiple myeloma patients: effects of therapy

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[166] has presented a novel GSH-depleting pro-oxidantbenzoyloxy dibenzyl carbonate (B2C)