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In addition, bromelain inhibited the iNOS and COX-2 expression in LPS-stimulated RAW 264.7 cells presumably as a result of inhibiting ERK (extracellular signal-regulated kinase) and p-38 phosphorylation (134)

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3D), in the gsh strain exposed to iron, there is a decrease in the transcriptional abundance of the ArgR repressor (EF0983, regulator of arginine metabolism) (31, 34, 35), and an increase in the expression levels of global transcription factors belonging to the LysR families (EF0644, EF0923, and EF2958) and TetR (EF0787 and EF2203), which are involved in basal metabolism, energy generation, and general stress responses

Colistin-resistant enterobacteriaceae infections: clinical and molecular characterization and analysis of in vitro synergy

For example, some people may be sensitive to plant saponins and develop inflammation after ingesting them