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References Hotez PJ, Fenwick A, Savioli L, Molyneux DH: Rescuing the bottom billion through control of neglected tropical diseases

Specifically, hypomethylation of UDP-glucose ceramide glucosyltransferase like 1 ( B3GNTL1 ) and homeobox D8 ( HOXD8 ), combined with hypermethylation of the homeobox B4 ( HOXB4 ), HOXA7 , integrin subunit alpha 4 ( ITGA4 ), zinc finger protein 808 ( ZNF808 ), and prostaglandin E receptor 4 ( PTGER4 ) genes, demonstrated significant accuracy for the detection of early-stage LUAD patients [121]