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Using products that maintain defined ingredient ratios and undergo quality testing may help reduce variables that could influence experimental outcomes

This is likely protected by interaction between dietary fibre and gut microbiota, as recently shown for mucus and barrier integrity in a mouse model, where mucus in synthetic microbiota-colonized fibre free diet mice was five to six times thinner than colonized mice fed the fibre rich diet (68)

continuously infused anesthetic agent(s) [1] 1st line: propofol (or, alternatively, midazolam) Either midazolam or propofol has traditionally been utilized as a front-line anesthetic

Outcome measures include neurological severity scoring, rotarod and beam walk performance, histological assessment of lesion volume, and immunohistochemistry for axonal markers and myelin basic protein