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2.3 Cognitive integrity Besides the MoCA test, individuals performed the tests of a Battery of Executive Functions, comprised by: two tests of short-term memory (verbal: Digit Span Forward, spatial: Corsi cubes Forward), two tests of working memory (verbal: Digit Span Backward and spatial: N -back test)

These metabolite changes suggest that the retrograde signal may involve altered activity of chromatin-modifying enzymes sensitive to these metabolites

The results of the BAP analysis are expressed in mol/l of the reduced ferric ions (25,26)

36 Strutyns'kyR

In addition to the upregulation of antioxidant defense induced by BHB, ketones also exert antioxidant function directly by increasing antioxidant activity [34]