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Furthermore, dextran sulfate sodium or trinitrobenzenesulfonic acid-mediated colitis in mice both demonstrated a mitigation of disease when treated with a TL1A antagonist antibody, manifested as reduction in weight loss, mortality, and histologic score (6, 9)

Lancet 329(8526):183188 Vendelboe TV, Harris P, Zhao Y, Walter TS, Harlos K, El Omari K, Christensen HE (2016) The crystal structure of human dopamine -hydroxylase at 2.9 resolution

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Compounding pharmacies and researchers typically use 250 to 500 micrograms per day as an exploratory range, not a clinically proven dose

doi: 10.1038/s41420-019-0222-2 125 ZhuJWangKZQChuCT