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Subsequently, they used Western blot analysis and RNA sequencing (RNA-seq) to demonstrate that the expression of GPX4 was declining in the early (MI 1 day) and middle (MI 1 week) stages of MI

Sato Y, Itagaki S, Kurokawa T, Ogura J, Kobayashi M, Hirano T, et al

The GCLC floxed mice (Cre-negative) shows lowered levels of glutathione in blood probably because introduced loxp sequences interrupt GCLC expression (Fig

includes DHL, PARXL, EFS, Aramex, and PANTOS

Another limitation to the study is the use of subjective and informant-based instruments (SRS, ABC, SEC, CGI) due to the lack of reliable and readily available objective or performance-based instruments to measure the clinical severity of ASD and treatment outcomes