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CagriSema combines an existing GLP-1 drug (semaglutide) with a new amylin analogue (cagrilintide) to recruit two hormone pathways

PMID: 30,951,714

In extracellular Ca 2+ -depleted medium (Figure 2E) or in the presence of 100 M lanthanum ions (La 3+ ), a non-selective calcium channel blocker, tBuOOH-induced [Ca 2+ ] i accumulation was completely inhibited (not shown), suggesting the occurrence of Ca 2+ entries under oxidative conditions