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M64 and MAC-545496 are two recently identified compounds currently in preclinical development, and both target bacterial biofilm formation

Steroidal lactones from Withania somnifera, an ancient plant for novel medicine

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Reoxygenation after hypoxia increases oxidant generation from enzymatic systems (e.g., xanthine oxidase, NADPH oxidases) and mitochondria, carrying an additional threat of oxidative injury to cells and tissues and potentially compromising organismal health and survival (Figure 1