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PMID: 39988211 J Pharmacol Sci Sustained increased CaMKII phosphorylation is involved in the impaired regression of isoproterenol-induced cardiac hypertrophy in rats

Due to the improved selection stringency, high producing clones could be generated in the absence of MSX using the GS KO host cell line, which was accompanied with a rapid cell line generation and reduced production of toxic metabolites such as ammonia and lactate