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Some users have reported side effects, including nausea, flushing, increased blood pressure, and darkening of existing moles

Pharmacologic management should be directed at each of these contributing factors

Lofgren IE, Herron KL, West KL, Zern TL, Brownbill RA, Ilich JZ, et al Weight loss favorably modifies anthropometrics and reverses the metabolic syndrome in premenopausal women J Am Coll Nutr