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Acknowledgements We would like to thank the staff of the Protein Research Core Facility at the Institute of Biophysics, Chinese Academy of Sciences (CAS), for their excellent technical assistance, particular for Drs Fuquan Yang and Peng Wu for their help in the mass spectroscopy experiment

They found that metastasis of the cancer cells relied on mitochondrial glutathione

HSPs interact with cytoskeletal proteins, such as filamin A (FlnA) that guides AR either toward the nucleus or cytoplasm by interacting with the hinge-region of AR [31]