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40 , D370D376 (2012)

This is among the more speculative areas of research

A second cohort of mice including WT, RAMP1 KO, RAMP3 KO, and RAMP1/3 KO genotypes confirmed that both RAMP1 and RAMP3 are individually essential for a full cagrilintide-induced neuronal activation response

Understanding the comparison means understanding that these are complementary strategies, not two versions of the same drug

After a 2 week screening period all eligible participants were randomly assigned to treatment groups receiving either a subcutaneous injection of 2.4 mg of semaglutide, 2.4 mg of cagrilintide, a combination of cagrilintide and semaglutide, a semaglutide placebo, or a cagrilintide placebo [2]