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doi: 10.3390/ijms23126580 73 Popawska-KitaATelejkoBSiewkoKKociuszko-ZdrodowskaMWawrusewicz-KurylonekNKrtowskiAet al

Months two to three: early indicators Subtle changes may become noticeable around the 4-8 week mark

These enzymes are involved in glycolysis, oxidative decarboxylation of pyruvate to acetyl-CoA, the tricarboxylic acid cycle, -oxidation of fatty acids, and alcohol metabolism