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Tapper 2 , Sardar Ansari 1 and Anna Lok 2 , (1)University of Michigan, (2)University of Michigan Medical Center Background: High-pressure tense ascites is the most debilitating form of ascites, requiring paracentesis to decompress

Storage and handling Before reconstitution (powder) Storage : Refrigerate at 2-8C (36-46F) Shelf life : 2-3 years when properly stored Stability : Very stable as lyophilized powder Travel : Can survive room temperature for short periods (days) After reconstitution (liquid) Storage : Refrigerate immediately at 2-8C Shelf life : 28 days with bacteriostatic water Stability : Degrades over time, use within 28 days Travel : Keep cold (use cooler with ice packs) Light : Protect from direct light (store in box) Handling tips Always use clean technique Don't contaminate vial top Use new needle each time Don't freeze Don't shake vigorously Mark reconstitution date on vial Common mistakes with 5mg vials Using wrong water Mistake : Using sterile water instead of bacteriostatic water

Each option adjusts default dosing ranges and units

Oral polystyrene consumption potentiates atherosclerotic lesion formation in ApoE / mice

At Cymbiotika, we ensure our formulations are produced in GMP-aligned facilities and tested for purity