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The mass spectrometer was operated in positive electrospray ionization mode at a collision energy of 12 V, spray voltage of 4000 V, cone and probe temperature of 350C, cone gas flow rate of 20 L min 1 , probe gas flow rate of 40 L min 1 , and nebulizer gas flow of 60 L min 1

AOD 9604 dosing fundamentals Standard AOD 9604 protocols use 250-500mcg daily via subcutaneous injection

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In many cases, differentiated malignant cells can reacquire stem-like features through dedifferentiation processes under selective pressures from the tumor microenvironment (TME) or therapy-induced stress