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Administration of hydrogen sulfide donors may help ameliorate cerebral BBB damage, most likely via MMP9 inhibition

Thus, further studies are needed to elucidate what role glutathione and inflammation could play in impaired oxidative muscle contractile functions and to better clarify the mechanisms (including the role of the liver and IL-6) underlying the reduction of GSH levels observed in the SOL muscle of young rats submitted to a short-term HFD

Neuroprotective effects of the novel brain-penetrating pyrrolopyrimidine antioxidants U-101033E and U-104067F against post-ischemic degeneration of nigrostriatal neurons

297 , G1232G1238 (2009)

If your model shows no effect, verify: (1) compound purity and correct amino acid sequence through independent analysis, (2) administration route appropriate for the peptide's pharmacokinetics, (3) dosing within the range established in analogous studies, and (4) treatment initiation timed to the injury or pathology phase the peptide's mechanism actually targets