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Sex differences in cognitive impairment in Alzheimers disease

2020;19:e13213

Insulin-like growth factor I (IGF-I) protects cells from apoptosis by Alzheimers V642I mutant amyloid precursor protein through IGF-I receptor in an IGF-binding protein-sensitive manner

Thus, the identity of ACSS catalyzing butyrate and crotonate activation requires further experimental validation

For example, chemotherapy-receiving breast cancer patients with elevated levels of p16INK4a senescent marker were found to experience most fatigue (Sanoff et al., 2014