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The enzyme of polyamine biosynthesis metabolism, ornithine decarboxylase (ODC, EC 4.1.1.17), showed a cause-effect relationship with Y-H morphogenesis in fungi [110]

Elacestrant was approved by FDA on January 27, 2023, for the treatment of estrogen receptor-positive, human epidermal growth factor receptor 2-negative, ESR1-mutated, advanced or metastatic breast cancer [6]

The cells were then treated with the corresponding drugs added to each well as needed for the experiment, and the cells were cultured for an additional 24 h

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