glutathione disulfide reductase oxyr human Oxidant Sensing by Reversible Disulfide

doi: 10.1038/s41467-017-02251-3 84 KwongBGaiSAElkhaderJWittrupKDIrvineDJ

Abbreviations SARS-CoV : Severe acute respiratory syndrome coronavirus MERS-CoV: Middle East respiratory syndrome coronavirus COVID-19: Coronavirus disease 2019 WHO: World Health Organization nCoV-19: Novel coronavirus HCoV-229E: Human coronavirus 229E HCoV-OC43: Human coronavirus OC43 SARS: Severe acute respiratory syndrome ICU: Intensive care unit HBOT: Hyperbaric oxygen therapy TNF: Tumor necrosis factor alpha TLR: Toll-like receptor NF-B: Nuclear factor B PE: Pulmonary embolism IHBO: Intermittent hyperbaric oxygen HBO: Hyperbaric oxygen BBB: Blood-brain barrier SO2: Oxygen saturation NAC: N-acetylcysteine NO2: Nitrogen dioxide OH: Hydroxyl radical CO3: Carbonate radical anion HOCl: Hypochlorous acid GSH: Glutathione IL10: Interleukin 10 ARDS: Acute respiratory distress syndrome CXCL8: Chemokine (C-X-C motif) ligand 8 CXCL10: C-X-C motif chemokine 10 CCL5: Chemokine (C-C motif) ligand 5 LDN: Low-dose naltrexone US: United States FDA: Food and Drug Administration TGF: Transforming growth factor TH: T helper cell G-CS: Granulocyte colony stimulating References Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H et al (2020) First case of 2019 novel coronavirus in the United States

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DCs express co-stimulatory ligands, and cytokines to drive the T-cell differentiation

More research is needed to understand the long-term effects on humans, importantly assessing any carcinogenic potential. If you do choose to use a topical hydroquinone treatment, Dr